Workshop
Workshop 8. Pharmacokinetic & Pharmacodynamic Simulation
- Time, Place and Language
- Nov 1 (Fri) 13:30-17:30, Room 9, Korean
- Moderator and Instructors
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- Moderator :
- Byung-Moon Choi (University of Ulsan, Korea)
- Instructors :
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- Yong-Hun Lee (University of Ulsan, Korea)
- Description
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This workshop aims to improve understanding of the basic principles of anesthetic pharmacology through simulation. Asan pump (version 2.1.3; Bionet Co. Ltd., Seoul, Korea, http://www.fit4nm.org/download, last accessed: Aug 27, 2012) will be used for simulation. The attendees can simulate propofol plasma concentrations and effect-site concentrations using the modified Marsh and Schnider models according to various dosing regimens. Characteristics of both pharmacokinetic models are discussed. Context sensitive decrement time, tpeak, and Vdpeak of fentanyl are also discussed.
- Learning Objectives
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- The attendees understand the pharmacokinetic parameters required for simulation.
- The attendees can explain the unit disposition function for predicting propofol disposition.
- The attendees can simulate propofol plasma concentrations and effect-site concentrations using the modified Marsh and Schnider models according to various dosing regimens.
- The attendees can calculate context sensitive decrement time, tpeak, and Vdpeak of fentanyl.